Buy Zoxan Injection Online
Zoxan injection only intramuscularly (in coxarthrosis) or intramuscularly in combination with the intraarticular injection of the agent (in knee osteoarthrosis). Physical examinations were made in control periods: before and immediately, 3, 6, and 12 months after treatment. Arthrosonography was used as an objective method for controlling the efficacy of the drug.
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The studies have demonstrated that alflutop substantially relieves pain, improves the function of the diseased joints in patients with OA. Arthrosonography has shown that the drug exerts an antiinflammatory effect, retards the progression of a pathological process in the joint. has been found to be more effective in knee OA than in hip OA, which is determined by that its combined use regimen may be used in knee OA. loflam 50ml
Zoxan Uses, Dosage, Side Effects and more
Zoxan is a synthetic 4-quinolone derivative with bactericidal activity against a wide range of gram-positive and gram-negative organism. It is active against most gram-negative aerobic bacteria including Enterobacteriaceae and Pseudomonas aeruginosa. Zoxan is also active against gram-positive aerobic bacteria including penicillinase producing, non-penicillinase producing and methicillin resistant Staphylococci. However, many strains of Streptococci are relatively resistant to the drug. The bactericidal activity of Zoxan results from interference with the enzyme DNA gyrase needed for the synthesis of bacterial DNA. The mode of action of Zoxan is different from other antibiotics like penicillins, cephalosporins, aminoglycosides, tetracyclines and for this reason it is observed that organisms resistant to these antibiotics are susceptible to Zoxan. Zoxan is well absorbed from the GIT after oral administration, and it is widely distributed into the body tissues and fluid. The half-life of Zoxan is 3.5 – 4.5 hours. About 30-50% of an oral dose of Zoxan is excreted in the urine within 24 hours as unchanged drug and active metabolites.
Zoxan (Eye/Ear) drops (Zoxan Hydrochloride ophthalmic solution) is a synthetic, sterile, multiple dose, antimicrobial for topical use. Zoxan is a fluoroquinolone antibacterial active against a broad spectrum of gram positive and gram-negative ocular pathogens. It is available as the monohydrochloride monohydrate salt of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)- 3-quinoline-carboxylic acid. It is a faint to light yellow crystalline powder with a molecular weight of 385.8. Its empirical formula is C17H18FN3O3.HCl.H2O.
Zoxan is a second generation fluoroquinolone that is active against many Gram negative and Gram positive bacteria. It produces its action through inhibition of bacterial DNA gyrase and topoisomerase IV. Zoxan binds to bacterial DNA gyrase with 100 times the affinity of mammalian DNA gyrase. There is no cross resistance between fluoroquinolones and other classes of antibiotics, so it may be of clinical value when other antibiotics are no longer effective. Ciprofloxain and its derivatives are also being investigated for its action against malaria, cancers, and AIDS.
The studies have demonstrated that alflutop substantially relieves pain, improves the function of the diseased joints in patients with OA. Arthrosonography has shown that the drug exerts an antiinflammatory effect, retards the progression of a pathological process in the joint. has been found to be more effective in knee OA than in hip OA, which is determined by that its combined use regimen may be used in knee OA. zoxan injection
| Attribute | Details |
|---|---|
| Trade Name | Zoxan |
| Availability | Prescription only |
| Generic | Ciprofloxacin |
| Ciprofloxacin Other Names | Ciprofloxacin, Ciprofloxacine, Ciprofloxacino, Ciprofloxacinum |
| Related Drugs | amoxicillin, prednisone, albuterol, doxycycline, cephalexin, metronidazole, azithromycin, clindamycin, ceftriaxone, levofloxacin |
| Weight | 500mg, 100mg/5ml |
| Type | Tablet, Eye Ear Drops, Eye Ointment, Eyeear Drops, Powder For Suspension |
| Formula | C17H18FN3O3 |
| Weight | Average: 331.3415 Monoisotopic: 331.133219662 |
| Protein binding | 20-40%. |
| Groups | Approved, Investigational |
| Therapeutic Class | 4-Quinolone preparations, Anti-diarrhoeal Antimicrobial drugs |
| Manufacturer | Fdc Limited, Opsonin Pharma Ltd |
| Available Country | India, Bangladesh |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Zoxan is used for the treatment of the following infections caused by sensitive bacteria:
Severe systemic infections: e.g; septicemia, bacteremia, peritonitis, infections in immunosuppressed patients with haematological or solid tumors and in patients in intensive care unit with specific problems such as infected burns.
Respiratory tract infections: Lobar and broncho pneumonia, acute and chronic bronchitis and empyema.
Urinary tract infections: Uncomplicated and complicated urethritis, cystitis, pyelonephritis, prostatitis and epididymitis.
Skin and soft tissue infections: Infected ulcers, wound infections, abscesses, cellulitis, otitis externa, erysipelas and infected burns.
Gastrointestinal infections: Enteric fever, infective diarrhea.
Infections of the biliary tract: Cholangitis, cholecystitis, empyema of the gall bladder.
Intra-abdominal infections: Peritonitis, intra abdominal abscesses.
Bone and joint infections: Osteomyelitis, septic arthritis.
Pelvic infections: Salpingitis, endometritis, pelvic inflammatory diseases.
Eye, ear, nose and throat infections: Otitis media, sinusitis, mastoiditis, tonsillitis.
Gonorrhoea: Urethral, rectal and pharyngeal gonorrhoea caused by beta-lactamase producing organism or organisms moderately sensitive to penicillin.
Zoxan (Eye/Ear) Solution is used for the treatment of infections caused by susceptible strains of the designated microorganisms in the conditions listed below:
Eye
Corneal Ulcers:
• Pseudomonas aeruginosa
• Serratia marcescens
• Staphylococcus aureus
• Staphylococcus epidermidis
• Streptococcus pneumonia
• Streptococcus (Viridans Group)
Conjunctivitis:
• Haemophilus influenza
• Staphylococcus aureus
• Staphylococcus epidermidis
• Streptococcus pneumoniae
Ear
Otitis externa, acute otitis media, cronic suppurative otitis media. Prophylaxis in otic surgeries such as mastoid surgery.
Zoxan is also used to associated treatment for these conditions: Acute Otitis Externa, Acute Otitis Externa caused by Pseudomonas Aeruginosa, Acute Otitis Media, Acute Sinusitis, Acute Uncomplicated Pyelonephritis, Acute exacerbation of chronic bronchitis caused by Moraxella catarrhalis, Bone and Joint Infections, Chronic Otitis Media, Complicated Intra-Abdominal Infections, Complicated Urinary Tract Infection, Conjunctivitis caused by Haemophilus influenzae, Conjunctivitis caused by Staphylococcus epidermidis, Corneal Ulcers caused by Serratia marcescens, Corneal Ulcers caused by Staphylococcus aureus, Corneal Ulcers caused by Staphylococcus epidermidis, Corneal Ulcers caused by Streptococcus Pneumoniae, Corneal Ulcers caused by Streptococcus Viridans Group, Corneal Ulcers caused by pseudomonas aeruginosa, Escherichia urinary tract infection, External ear infection NOS, Febrile Neutropenia, Infection of the outer ear caused by susceptible bacteria, Infectious diarrhea, Lower respiratory tract infection caused by Enterobacter cloacae, Lower respiratory tract infection caused by Escherichia coli, Lower respiratory tract infection caused by Haemophilus influenzae, Lower respiratory tract infection caused by Haemophilus parainfluenzae, Lower respiratory tract infection caused by Klebsiella pneumoniae, Lower respiratory tract infection caused by Proteus mirabilis, Lower respiratory tract infection caused by penicillin-susceptible Streptococcus pneumoniae, Nosocomial Pneumonia, Otitis Media (OM), Otitis Media, Purulent, Plague caused by Yersinia pestis, Skin Infections, Typhoid fever caused by Salmonella typhi, UTI caused by Citrobacter diversus, UTI caused by Citrobacter frendii, UTI caused by Entercococcus faecalis, UTI caused by Enterobacter cloacae, UTI caused by Klebsiella pneumoniae, UTI caused by Morganella morganii, UTI caused by Proteus mirabilis, UTI caused by Providencia rettgeri, UTI caused by Pseudomonas aeruginosa, UTI caused by Serratia marcescens, UTI caused by methicillin-susceptible Staphylococcus epidermidis, Uncomplicated Urinary Tract Infections, Acute otitis externa caused by Staphylococcus aureus, Acute, uncomplicated Cystitis caused by Escherichia coli, Acute, uncomplicated Cystitis caused by Staphylococcus saprophyticus, Chronic Prostatitis caused by Escherichia coli, Chronic Prostatitis caused by Proteus mirabilis, Complicated Pyelonephritis caused by Escherichia coli, Complicated Urinary Tract Infection caused by Escherichia Coli, Inhaled anthrax caused by Bacillus anthracis, Uncomplicated Gonorrhea caused by Neisseria gonorrhoeae
The necessity and high efficiency of repeated courses of alflutop therapy are shown intramuscularly (in coxarthrosis) or intramuscularly in combination with the intraarticular injection of the agent (in knee osteoarthrosis). Physical examinations were made in control periods: before and immediately, 3, 6, and 12 months after treatment. Arthrosonography was used as an objective method for controlling the efficacy of the drug. The studies have demonstrated that alflutop substantially relieves pain, improves the function of the diseased joints in patients with OA. Arthrosonography zoxan injection

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